OCEAN project
Our results confirm that an immersive game involving complex motor activities for pro-social benefit was enjoyed and well tolerated. Gamers with a history of TBI demonstrated improved subicular and CA3 volumes of the left hippocampus relative to active controls. These promising results have implications for early intervention designed for social, physical and cognitive engagement in single player and group player settings among those at risk for mild cognitive impairment and ADRD.
Authors
- John W. Krakauer (ORCID: https://orcid.org/0000-0002-4316-1846)
- Kyle Moored (ORCID: https://orcid.org/0000-0001-8938-6357)
- Kylie H. Alm
- Michelle C. Carlson (ORCID: https://orcid.org/0000-0003-2465-7421)
- Emily A. Richards
- Matthew E. Peters (ORCID: https://orcid.org/0000-0002-5668-4566)
- Arnold Bakker
- Omar Ahmad
- Promit Roy
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- NeuroNascent (United States) (US)
- Imation (United States) (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_102355
- Primary Topic
- Traumatic Brain Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00