Whole‐genome variant analysis of Alzheimer's disease biomarker traits
Our study highlights the contribution of both PRS and rare variants in ABCA7, ECSIT, and ADPRHL1 to AD biomarker traits. These findings provide insights into the pathophysiology of AD and may lead to novel targets for diagnosis and therapy.
Authors
- Bing Tang (ORCID: https://orcid.org/0000-0001-5859-8250)
- Xinxin Liao (ORCID: https://orcid.org/0000-0002-3838-2097)
- Yiliang Liu (ORCID: https://orcid.org/0000-0001-7703-7512)
- Xuewen Xiao
- Bin Jiao
- Lu Shen
- Shilin Luo
- Jinchen Li
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_099640
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00