Eye diseases and dementia: association because of pathogenesis or visual impairment?

AMD is associated with a mildly reduced risk of Alzheimer's dementia when controlling for blindness. Prior reports linking AMD to dementia likely reflect the impact of blindness rather than shared pathology. This protective effect may be due to AMD treatments like AREDS2 vitamins, which support cognitive health.

Authors

Institutions

Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70860_099176
Primary Topic
Ophthalmology and Visual Impairment Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Eye diseases and dementia: association because of pathogenesis or visual impairment?

David A. Kaelber, Pauline Terebuh, Xinyu Gu, Rong Xu et al.
Alzheimer s & Dementia
Ophthalmology and Visual Impairment Studies
article

Eye diseases and dementia: association because of pathogenesis or visual impairment?

David A. Kaelber, Pauline Terebuh, Xinyu Gu, Rong Xu, Pamela Davis
article en

Abstract

AMD is associated with a mildly reduced risk of Alzheimer's dementia when controlling for blindness. Prior reports linking AMD to dementia likely reflect the impact of blindness rather than shared pathology. This protective effect may be due to AMD treatments like AREDS2 vitamins, which support cognitive health.

Alzheimer s & DementiaVol. 21(S6)
University School (US), Case Western Reserve University (US)
Gender equality
Openalex Percentile: Top 31%
Ophthalmology and Visual Impairment Studies
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.