Association of Midlife Vascular Health with Dementia‐Free Life Expectancy and Years Lived with Dementia
A higher burden of midlife vascular risk factors is associated with earlier dementia and a reduction in dementia-free life expectancy by up to 13 years with an additional 2-4 years with dementia, this is primarily due to higher mortality. These findings highlight the urgent need for midlife vascular health interventions to delay dementia onset and promote brain health.
Authors
- Michael Fang (ORCID: https://orcid.org/0000-0003-2849-1780)
- Pamela L. Lutsey (ORCID: https://orcid.org/0000-0002-1572-1340)
- Richey Sharrett
- Thomas H. Mosley
- Rebecca F. Gottesman
- Jiaqi Hu
- Josef Coresh
- Jordan Weiss
- Elizabeth Selvin
Institutions
- University of Minnesota (US)
- Johns Hopkins University (US)
- Jackson Memorial Hospital (US)
- University of Mississippi Medical Center (US)
- National Institute of Neurological Disorders and Stroke (US)
- New York University (US)
- Tsinghua University (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_104468
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00