Unveiling the genetic relationship between Alzheimer’s disease and chronic pain‐related disorders
Our study reveals a significant genetic correlation between AD and CPDs, except for ankylosis and rheumatoid arthritis, and the causal effects of MCP on AD. It identified significant genetic overlap and shared genes by AD across the CPDs, implicating shared biological mechanisms.
Authors
- Laws Sg
- Olasunkanmi David Bamidele (ORCID: https://orcid.org/0000-0002-5902-5531)
- Emmanuel O Adewuyi (ORCID: https://orcid.org/0000-0002-4533-0340)
- Ayeisha Milligan Armstrong (ORCID: https://orcid.org/0000-0001-6749-6184)
- Eleanor O’Brien
- Tenielle Porter
- Giuseppe Verdile
Institutions
- Edith Cowan University (AU)
- University of Ilorin (NG)
- Curtin University (AU)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70861_108281
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00