Resolution of chronic spontaneous urticaria and atopic dermatitis with upadacitinib in a patient with Crohn's disease

Inflammatory bowel disease (IBD) is a chronic immune-mediated disorder of the gastrointestinal tract that includes both Crohn's disease and ulcerative colitis. IBD not only causes gastrointestinal symptoms but is also associated with extraintestinal manifestations like inflammatory skin diseases. Recently, upadacitinib, a selective Janus kinase 1 inhibitor, was approved for the treatment of both IBD and atopic dermatitis.

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Publication Details

Journal
Canadian Journal of General Internal Medicine
Published
2025-12-01
DOI
https://doi.org/10.3138/cjgim.2025.0033
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
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article

Resolution of chronic spontaneous urticaria and atopic dermatitis with upadacitinib in a patient with Crohn's disease

V W Huang, Nikhila Butani, Hermenio Lima
Canadian Journal of General Internal Medicine
Dermatology and Skin Diseases
article

Resolution of chronic spontaneous urticaria and atopic dermatitis with upadacitinib in a patient with Crohn's disease

V W Huang, Nikhila Butani, Hermenio Lima
article en

Abstract

Inflammatory bowel disease (IBD) is a chronic immune-mediated disorder of the gastrointestinal tract that includes both Crohn's disease and ulcerative colitis. IBD not only causes gastrointestinal symptoms but is also associated with extraintestinal manifestations like inflammatory skin diseases. Recently, upadacitinib, a selective Janus kinase 1 inhibitor, was approved for the treatment of both IBD and atopic dermatitis.

Canadian Journal of General Internal MedicineVol. 20(4)
Mount Sinai Hospital (CA), University of Toronto (CA), McMaster University Medical Centre (CA), Hamilton Regional Laboratory Medicine Program (CA), McMaster University (CA)
Good health and well-being
Openalex Percentile: Top 25%
Dermatology and Skin Diseases
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