Synthesis of Sulfonated Trimer Peptides to Discover Potential Drug Candidates Targeting Amyloid‐β in Alzheimer's Disease

As a result, a total of 27 sulfonated trimer peptides were successfully synthesized and purified. Through subsequent efficacy validation of the synthesized trimer peptides, the essential contribution of sulfonation to amyloid-β targeting will be elucidated.

Authors

Minhae Cha
Sunghyun Kim
YoungSoo Kim

Institutions

Incheon National University (KR)
Yonsei University (KR)
Solid (South Korea) (KR)

Publication Details

Journal: Alzheimer s & Dementia
Published: 2025-12-01
DOI: https://doi.org/10.1002/alz70861_108192
Primary Topic: Chemical Synthesis and Analysis
Type: article
Field-Weighted Citation Impact: 0.00

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article

Synthesis of Sulfonated Trimer Peptides to Discover Potential Drug Candidates Targeting Amyloid‐β in Alzheimer's Disease

Minhae Cha, Sunghyun Kim, YoungSoo Kim

Dec 1, 2025

Alzheimer s & Dementia

Chemical Synthesis and Analysis

article

Synthesis of Sulfonated Trimer Peptides to Discover Potential Drug Candidates Targeting Amyloid‐β in Alzheimer's Disease

Minhae Cha, Sunghyun Kim, YoungSoo Kim

December 1, 2025article en

Abstract

Alzheimer s & DementiaVol. 21(S7)

Incheon National University (KR), Yonsei University (KR), Solid (South Korea) (KR)

Good health and well-being

Openalex Percentile: Top 37%

Chemical Synthesis and Analysis

DOI Open Access PDF OpenAlex

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