Enhanced therapeutic efficacy of repeated bone marrow–derived MSC administration in a murine model of pulmonary fibrosis
Repeated hBMSCs administration enhances therapeutic efficacy in silicosis by improving cell persistence and attenuating fibrosis, partly through ZC3H4-mediated regulation of macrophages.
Authors
- Zihan Zhou (ORCID: https://orcid.org/0000-0002-4265-7145)
- Jie Huang (ORCID: https://orcid.org/0000-0002-3917-912X)
- Shuhua Han
- Jiawei Ding (ORCID: https://orcid.org/0000-0001-7417-7085)
- Chao Jie
- Yuanfang Duan
Institutions
- Zhongda Hospital Southeast University (CN)
- The First People’s Hospital of Lianyungang (CN)
- Southeast University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1186/s13287-025-04859-5
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00