Non-clostridial gas gangrene due to Anaerococcus tetradius following a cesarean section: A case report

A 25-year-old healthy woman was admitted to our hospital with fever and abdominal pain. Abdominal contrast-enhanced computed tomography revealed a fluid collection with foamy gas formation extending from both rectus abdominis muscles to the subcutaneous tissue. Antimicrobial therapy with meropenem (3 g/day), clindamycin (1800 mg/day), and daptomycin (300 mg/day) was initiated as empiric therapy. Subcutaneous abscess culture revealed gram-positive cocci, which was identified as Anaerococcus tetradius. Histopathological examination of the necrotic tissue showed skeletal muscle necrosis. On the basis of these findings, the patient was diagnosed with Non-Clostridial Gas Gangrene (NCGG) due to A. tetradius. We report a novel case of NCGG caused by A. tetradius following a cesarean section in an immunocompetent patient. Although A. tetradius has been detected in clinical specimens, cases of human infections are extremely rare. Clinicians should consider A. tetradius infection as a complication of a cesarean section.

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Publication Details

Journal
The Brazilian Journal of Infectious Diseases
Published
2025-12-23
DOI
https://doi.org/10.1016/j.bjid.2025.104609
Primary Topic
Amoebic Infections and Treatments
Type
article
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article

Non-clostridial gas gangrene due to Anaerococcus tetradius following a cesarean section: A case report

Kazufumi Hiramatsu, Tomonori Yamada, Takehiro Hashimoto, Mamiko Okamoto et al.
The Brazilian Journal of Infectious Diseases
Amoebic Infections and Treatments
article

Non-clostridial gas gangrene due to Anaerococcus tetradius following a cesarean section: A case report

Kazufumi Hiramatsu, Tomonori Yamada, Takehiro Hashimoto, Mamiko Okamoto, Eiji Kobayashi
article en

Abstract

A 25-year-old healthy woman was admitted to our hospital with fever and abdominal pain. Abdominal contrast-enhanced computed tomography revealed a fluid collection with foamy gas formation extending from both rectus abdominis muscles to the subcutaneous tissue. Antimicrobial therapy with meropenem (3 g/day), clindamycin (1800 mg/day), and daptomycin (300 mg/day) was initiated as empiric therapy. Subcutaneous abscess culture revealed gram-positive cocci, which was identified as Anaerococcus tetradius. Histopathological examination of the necrotic tissue showed skeletal muscle necrosis. On the basis of these findings, the patient was diagnosed with Non-Clostridial Gas Gangrene (NCGG) due to A. tetradius. We report a novel case of NCGG caused by A. tetradius following a cesarean section in an immunocompetent patient. Although A. tetradius has been detected in clinical specimens, cases of human infections are extremely rare. Clinicians should consider A. tetradius infection as a complication of a cesarean section.

The Brazilian Journal of Infectious DiseasesVol. 30(1)
Oita University (JP), Oita University Hospital (JP)
Good health and well-being
Openalex Percentile: Top 31%
Amoebic Infections and Treatments
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