Surgical site infections: A narrative review of risk factors, prevention, and emerging innovations

Surgical site infections (SSIs) are a frequent worry after surgery, caused by several interactions and relationships involving the patient and the surgical process. The investigated primary factors, which play an important role in SSIs, are the traditional risk factors of diabetes, obesity, and smoking, and the emerging risk factors for metabolic syndrome, anemia, and hypoproteinemia. Effective SSI prevention methods in the operating room include timely prophylactic antibiotic use, strict aseptic protocols, and adequate perioperative care. In this narrative review, we have addressed emerging methods such as the use of biodegradable electrically active sutures and antimicrobial photodynamic therapy to reduce the rate of SSIs. There are still difficulties in giving optimal and quick treatment to many patients, especially in India, where the resources and use of new knowledge are restricted. We believe that the only way to address these challenges is through engagement and incorporation of patient-related factors, process improvement, the role of technology, creation and implementation of systematic protocols, adequately funded health policies, and equipment can serve to improve patient outcomes and reduce the incidence of SSIs ultimately.

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Publication Details

Journal
Journal of Laboratory Physicians
Published
2025-12-23
DOI
https://doi.org/10.25259/jlp_219_2025
Primary Topic
Surgical site infection prevention
Type
article
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article

Surgical site infections: A narrative review of risk factors, prevention, and emerging innovations

Anup A Zade, Imran Ali Khan, Shailabh Shailabh, Bhagyesh Sapkale
Journal of Laboratory Physicians
Surgical site infection prevention
article

Surgical site infections: A narrative review of risk factors, prevention, and emerging innovations

Anup A Zade, Imran Ali Khan, Shailabh Shailabh, Bhagyesh Sapkale
article en

Abstract

Surgical site infections (SSIs) are a frequent worry after surgery, caused by several interactions and relationships involving the patient and the surgical process. The investigated primary factors, which play an important role in SSIs, are the traditional risk factors of diabetes, obesity, and smoking, and the emerging risk factors for metabolic syndrome, anemia, and hypoproteinemia. Effective SSI prevention methods in the operating room include timely prophylactic antibiotic use, strict aseptic protocols, and adequate perioperative care. In this narrative review, we have addressed emerging methods such as the use of biodegradable electrically active sutures and antimicrobial photodynamic therapy to reduce the rate of SSIs. There are still difficulties in giving optimal and quick treatment to many patients, especially in India, where the resources and use of new knowledge are restricted. We believe that the only way to address these challenges is through engagement and incorporation of patient-related factors, process improvement, the role of technology, creation and implementation of systematic protocols, adequately funded health policies, and equipment can serve to improve patient outcomes and reduce the incidence of SSIs ultimately.

Journal of Laboratory PhysiciansVol. 0
Jawaharlal Nehru Medical College (IN)
Good health and well-being
Openalex Percentile: Top 27%
Surgical site infection prevention
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Surgical site infections: A narrative review of risk factors, prevention, and emerging innovations — Anup A Zade, Imran Ali Khan, et al. · Journal of Laboratory Physicians (2025) | TGRS Research Map | TGRS