Outcomes of Modified Extracorporeal Membrane Oxygenation Using A Cardiopulmonary Bypass Circuit in Postcardiotomy Children With Congenital Heart Disease—A Ten-Year Experience From a Resource-Limited Center

<b>Objectives:</b> Extracorporeal membrane oxygenation (ECMO) plays a crucial role in the outcome of children following surgery for congenital heart disease. However, its availability and affordability are minimal across the globe. We present our experience with a modified ECMO circuit using a conventional cardiopulmonary bypass (CPB) oxygenator in postcardiotomy children following surgical repair of congenital heart disease. <b>Material and Methods:</b> The data were collected retrospectively by screening all pediatric cardiac surgery patients from June 2014 to December 2024. A total of 3,527 patients underwent surgery for congenital heart disease. The modified ECMO circuit was used in a total of 34/3,527 (0.9%) patients following congenital cardiac surgery during this period. Data on demographics, surgical details, indications, and duration of modified ECMO, complications, successful decannulation, and hospital discharge were collected from electronic health records. Kaplan-Meier was used to plot hospital stay and in-hospital mortality with respect to successful decannulation. <b>Results:</b> The median duration of support with the modified ECMO circuit was 39 hours (IQR 24-56). Successful decannulation was accomplished in 20/34 patients (58.8%), and 11/34 patients (32.3%) went home alive from the hospital. Complications encountered included renal dysfunction (39.4% [13/34]), bleeding (35.2% [12/34]), seizures (8.8% [3/34]), and stroke (5.8% [2/34]). <b>Conclusion:</b> The modified ECMO circuit, derived from the conventional CPB circuit, offers a cost-effective solution for short-term cardiac support in pediatric cardiac surgery. Survival rates and complications suggest its viability, particularly in resource-limited settings.

Authors

Institutions

Publication Details

Journal
World Journal for Pediatric and Congenital Heart Surgery
Published
2025-12-23
DOI
https://doi.org/10.1177/21501351251394370
Primary Topic
Mechanical Circulatory Support Devices
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Outcomes of Modified Extracorporeal Membrane Oxygenation Using A Cardiopulmonary Bypass Circuit in Postcardiotomy Children With Congenital Heart Disease—A Ten-Year Experience From a Resource-Limited Center

Jahnavi Narayanan, Kaushik Jothinath, Naveen Raj Srinivasan, Sumathi Kandaswamy et al.
World Journal for Pediatric and Congenital Heart Surgery
Mechanical Circulatory Support Devices
article

Outcomes of Modified Extracorporeal Membrane Oxygenation Using A Cardiopulmonary Bypass Circuit in Postcardiotomy Children With Congenital Heart Disease—A Ten-Year Experience From a Resource-Limited Center

Jahnavi Narayanan, Kaushik Jothinath, Naveen Raj Srinivasan, Sumathi Kandaswamy, Pavithra Ramanath, Vijayakumar Raju, Sreja Gangadharan, Janarthanan Maniyarasu, Sridevi Sundarajan, Vinoth Kumar Sundarajan, Umapathy Jeganathan
article en

Abstract

<b>Objectives:</b> Extracorporeal membrane oxygenation (ECMO) plays a crucial role in the outcome of children following surgery for congenital heart disease. However, its availability and affordability are minimal across the globe. We present our experience with a modified ECMO circuit using a conventional cardiopulmonary bypass (CPB) oxygenator in postcardiotomy children following surgical repair of congenital heart disease. <b>Material and Methods:</b> The data were collected retrospectively by screening all pediatric cardiac surgery patients from June 2014 to December 2024. A total of 3,527 patients underwent surgery for congenital heart disease. The modified ECMO circuit was used in a total of 34/3,527 (0.9%) patients following congenital cardiac surgery during this period. Data on demographics, surgical details, indications, and duration of modified ECMO, complications, successful decannulation, and hospital discharge were collected from electronic health records. Kaplan-Meier was used to plot hospital stay and in-hospital mortality with respect to successful decannulation. <b>Results:</b> The median duration of support with the modified ECMO circuit was 39 hours (IQR 24-56). Successful decannulation was accomplished in 20/34 patients (58.8%), and 11/34 patients (32.3%) went home alive from the hospital. Complications encountered included renal dysfunction (39.4% [13/34]), bleeding (35.2% [12/34]), seizures (8.8% [3/34]), and stroke (5.8% [2/34]). <b>Conclusion:</b> The modified ECMO circuit, derived from the conventional CPB circuit, offers a cost-effective solution for short-term cardiac support in pediatric cardiac surgery. Survival rates and complications suggest its viability, particularly in resource-limited settings.

World Journal for Pediatric and Congenital Heart Surgery
G. Kuppuswamy Naidu Memorial Hospital (IN)
Openalex Percentile: Top 43%
Mechanical Circulatory Support Devices
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.