Monocyte telomere length as a novel biomarker of macular atrophy and response to anti-VEGF therapy in age-related macular degeneration

These findings highlight monocyte telomere length as a potential biomarker for predicting macular atrophy progression and treatment outcomes in AMD. Further research is needed to confirm these associations and to explore sex/ethnic disparities in telomere length in this disease.

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Publication Details

Journal
Russian Annals of Ophthalmology
Published
2025-12-23
DOI
https://doi.org/10.17116/oftalma202514106152
Primary Topic
Telomeres, Telomerase, and Senescence
Type
article
Field-Weighted Citation Impact
0.00
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article

Monocyte telomere length as a novel biomarker of macular atrophy and response to anti-VEGF therapy in age-related macular degeneration

A.S. Khalatyan, D.D. Zhdanov, K.S. Avetisov, Yu.A. Gladilina et al.
Russian Annals of Ophthalmology
Telomeres, Telomerase, and Senescence
article

Monocyte telomere length as a novel biomarker of macular atrophy and response to anti-VEGF therapy in age-related macular degeneration

A.S. Khalatyan, D.D. Zhdanov, K.S. Avetisov, Yu.A. Gladilina, Yu. Yusef, V.G. Blinova, A.N. Shishparenok
article en

Abstract

These findings highlight monocyte telomere length as a potential biomarker for predicting macular atrophy progression and treatment outcomes in AMD. Further research is needed to confirm these associations and to explore sex/ethnic disparities in telomere length in this disease.

Russian Annals of OphthalmologyVol. 141(6)
Federal State Scientific Institution Research Institute of Eye Diseases (RU), Institute of Biomedical Chemistry (RU)
Good health and well-being
Openalex Percentile: Top 34%
Telomeres, Telomerase, and Senescence
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