The diagnostic value of semiology, <scp>EEG</scp> and <scp>MRI</scp> in new‐onset pediatric bilateral tonic–clonic seizures: A multimodal analysis

Children who experience a first-time convulsive seizure need an accurate diagnosis to guide appropriate treatment. In our study of 249 children with new onset bilateral tonic-clonic seizures, we found that no single diagnostic tool, whether seizure description, EEG, or MRI, was sufficient on its own. However, when these tools were combined, clinicians were able to correctly determine the seizure type in more than 80% of cases. We also found that some signs typically considered focal, such as head turning, may still appear in generalized seizures. These findings underscore the importance of a multimodal approach to ensure optimal diagnosis and treatment planning for children with new onset seizures.

Authors

Institutions

Publication Details

Journal
Epilepsia Open
Published
2025-12-23
DOI
https://doi.org/10.1002/epi4.70203
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

The diagnostic value of semiology, EEG and MRI in new‐onset pediatric bilateral tonic–clonic seizures: A multimodal analysis

Wassim Nasreddine, Ayman Beydoun, Jaafar Wazne, Abdel Rahman Shatila et al.
Epilepsia Open
Epilepsy research and treatment
article

The diagnostic value of semiology, EEG and MRI in new‐onset pediatric bilateral tonic–clonic seizures: A multimodal analysis

Wassim Nasreddine, Ayman Beydoun, Jaafar Wazne, Abdel Rahman Shatila, Ahmad Beydoun, Ghassan Hmeimess, Badiee Moussa, Huda Abboodi
article en

Abstract

Children who experience a first-time convulsive seizure need an accurate diagnosis to guide appropriate treatment. In our study of 249 children with new onset bilateral tonic-clonic seizures, we found that no single diagnostic tool, whether seizure description, EEG, or MRI, was sufficient on its own. However, when these tools were combined, clinicians were able to correctly determine the seizure type in more than 80% of cases. We also found that some signs typically considered focal, such as head turning, may still appear in generalized seizures. These findings underscore the importance of a multimodal approach to ensure optimal diagnosis and treatment planning for children with new onset seizures.

Epilepsia OpenVol. 11(1)
University of Balamand (LB), Rafik Hariri University Hospital (LB), University Medical Center Rizk Hospital (LB), American University of Beirut Medical Center (LB)
Openalex Percentile: Top 36%
Epilepsy research and treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.