Endothelial Cells in Lymphomas

Endothelial cells play a complex role in lymphoma by becoming genetically abnormal alongside tumor cells, forming blood vessels that fuel lymphoma growth and invasiveness, and contributing to the establishment of an immunosuppressive tumor microenvironment. Because of their significant role in lymphoma growth and immune evasion, endothelial cells and the processes that regulate them are being explored as attractive targets for new anti-angiogenic therapies and immunotherapies to overcome the limitations of anti-angiogenic therapy in lymphoma treatment.