Comparative renal safety: potassium-competitive acid blockers vs proton pump inhibitors

P-CABs showed a lower risk of renal function decline compared with PPIs, suggesting that P-CABs may be a safer alternative for long-term acid suppression. Further studies incorporating other P-CABs and PPIs are needed to confirm these findings.

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Publication Details

Journal
Clinical Kidney Journal
Published
2025-12-19
DOI
https://doi.org/10.1093/ckj/sfaf400
Primary Topic
Potassium and Related Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparative renal safety: potassium-competitive acid blockers vs proton pump inhibitors

Jung Eun Lee, Hye Ryoun Jang, Seung Min Song, Sungmi Kim et al.
Clinical Kidney Journal
Potassium and Related Disorders
article

Comparative renal safety: potassium-competitive acid blockers vs proton pump inhibitors

Jung Eun Lee, Hye Ryoun Jang, Seung Min Song, Sungmi Kim, Wooseong Huh, Minyoung Jang, Minhyung Kim, Junseok Jeon, Kyungho Lee
article en

Abstract

P-CABs showed a lower risk of renal function decline compared with PPIs, suggesting that P-CABs may be a safer alternative for long-term acid suppression. Further studies incorporating other P-CABs and PPIs are needed to confirm these findings.

Clinical Kidney JournalVol. 19(2)
Korea University Medical Center (KR), Samsung Medical Center (KR), St. Mary's Hospital (US)
Good health and well-being
Openalex Percentile: Top 29%
Potassium and Related Disorders
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