Strengths and Limitations of Sodium Lauryl Sulfate as an Irritant Control in Patch Testing

While SLS can indicate skin irritability for certain allergens, it is not a universal marker. Our large-scale analysis supports binary SLS classification and provides a robust evidence base for the ongoing debate on whether and how irritant controls should be used in patch testing.

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Publication Details

Journal
Contact Dermatitis
Published
2025-12-22
DOI
https://doi.org/10.1111/cod.70075
Primary Topic
Contact Dermatitis and Allergies
Type
article
Field-Weighted Citation Impact
0.00

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article

Strengths and Limitations of Sodium Lauryl Sulfate as an Irritant Control in Patch Testing

C. Skudlik, Nicola Wagner, Burkhard Kreft, Moritz M. Hollstein et al.
Contact Dermatitis
Contact Dermatitis and Allergies
article

Strengths and Limitations of Sodium Lauryl Sulfate as an Irritant Control in Patch Testing

C. Skudlik, Nicola Wagner, Burkhard Kreft, Moritz M. Hollstein, Susann Forkel, Annice Heratizadeh, Timo Buhl, Andréa Carla Bauer, Mathias Sulk, H. Löffler, Silke S. Matzke, Guido Heine
article en

Abstract

While SLS can indicate skin irritability for certain allergens, it is not a universal marker. Our large-scale analysis supports binary SLS classification and provides a robust evidence base for the ongoing debate on whether and how irritant controls should be used in patch testing.

Contact DermatitisVol. 94(4)
Danube Private University (AT), Osnabrück University (DE), Friedrich-Alexander-Universität Erlangen-Nürnberg (DE), Medizinische Hochschule Hannover (DE), Universitätsklinikum Erlangen (DE), University Hospital Münster (DE), University Hospital Schleswig-Holstein (DE), University Hospital Leipzig (DE), SLK-Kliniken Heilbronn (DE), University Hospital Carl Gustav Carus (DE), Martin Luther University Halle-Wittenberg (DE), University of Göttingen (DE), University of Lübeck (DE)
Universitätsmedizin Göttingen
Reduced inequalities
Openalex Percentile: Top 25%
Contact Dermatitis and Allergies
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