Microbial dysbiosis in melasma through community profiling
Our study indicates that there are significant differences in the microbiome between lesional and peri-lesional areas of melasma subjects, with associated changes in microbial community structures. Additionally, the observed changes were seen to correlate with measured clinical parameters. These findings provide the opportunity to further probe the nature of host and microbiome links that may underlie the phenotypic manifestation, as well as provide effective routes for managing this recalcitrant disorder.
Authors
- Sarah Paterson (ORCID: https://orcid.org/0000-0002-6512-1888)
- Arindam Roy
- Chandraprabha Doraiswamy
- David Arnold (ORCID: https://orcid.org/0000-0003-1269-4516)
- Aparna Damle
- Deepshikha Singh
- Maitreyee Dutta
- Savitha Rajkumar
- Nirmala Nair (ORCID: https://orcid.org/0000-0001-7691-2397)
- Tony Dadd
- Brian Potterf
- Nagasuma Chandra (ORCID: https://orcid.org/0000-0002-9939-8439)
- Mukta Sachdev
- Bharat Cheviti
- Yugandhar Reddy B.S
- Paul Van-Der Logt
- Nagalakshmi Surendra
Institutions
- Unilever (United Kingdom) (GB)
- Unilever (Netherlands) (NL)
- MS Clinical Research (India) (IN)
- Unilever (India) (IN)
- Preusser Research Group (US)
- Unilever Foods Innovation Centre (NL)
- Data Power Decisions (United States) (US)
- Indian Institute of Science Bangalore (IN)
Publication Details
- Journal
- Frontiers in Microbiomes
- Published
- 2025-12-22
- DOI
- https://doi.org/10.3389/frmbi.2025.1505565
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00