Facile synthesis of multisubstituted 2,3-dihydrofurans <i>via</i> intermolecular cyclization of enals or alkyl/aryl aldehydes with acyl-stabilized sulfur ylides
Reported herein is a general strategy for the synthesis of multisubstituted 2,3-dihydrofurans through pivalic acid- and DABCO-promoted intermolecular cyclization of aldehydes with acyl-stabilized sulfur ylides. Following this process, a series of 2,3-dihydrofuran derivatives were prepared in good yields with a broad substrate scope and excellent functional group compatibility under mild conditions.
Authors
- Yin Su
- Ziyi Sun
- Liang Fu
- Quansheng Zhao
Institutions
- Anhui Normal University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1039/d5cc06219e
- Citations
- 1
- Primary Topic
- Cyclopropane Reaction Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.94