Higher serum IgG4 levels correlate with better quality of life in mild Graves’ orbitopathy: a preliminary report

This study highlights the significant impairment in the quality of life experienced by patients with mild GO and identifies serum IgG4 as a promising indicator for evaluating disease chronicity and quality of life, which may help guide different treatment strategies. Further prospective and basic studies are required to explore the role of IgG4 in the pathogenesis of GO.

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Publication Details

Journal
Endocrine Connections
Published
2025-12-23
DOI
https://doi.org/10.1530/ec-25-0582
Primary Topic
Ophthalmology and Eye Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Higher serum IgG4 levels correlate with better quality of life in mild Graves’ orbitopathy: a preliminary report

Chun-Hsien Lin, Yen-Chung Hsiue, Ching Lu, Shyang-Rong Shih et al.
Endocrine Connections
Ophthalmology and Eye Disorders
article

Higher serum IgG4 levels correlate with better quality of life in mild Graves’ orbitopathy: a preliminary report

Chun-Hsien Lin, Yen-Chung Hsiue, Ching Lu, Shyang-Rong Shih, Chung-Wei Lee, Yi-Chieh Lee, Kang-Chih Fan, Chia-Hung Lin, Chung-Yi Yang, Yi-Hsuan Wei, Tse-Ying Huang, I-Weng Yen
article en

Abstract

This study highlights the significant impairment in the quality of life experienced by patients with mild GO and identifies serum IgG4 as a promising indicator for evaluating disease chronicity and quality of life, which may help guide different treatment strategies. Further prospective and basic studies are required to explore the role of IgG4 in the pathogenesis of GO.

Endocrine ConnectionsVol. 15(1)
National Taiwan University (TW), E-Da Hospital (TW), Taiwan Semiconductor Manufacturing Company (Taiwan) (TW), National Taiwan University Hospital (TW), I-Shou University (TW)
Openalex Percentile: Top 30%
Ophthalmology and Eye Disorders
DOIOpen Access PDFOpenAlex
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Higher serum IgG4 levels correlate with better quality of life in mild Graves’ orbitopathy: a preliminary report — Chun-Hsien Lin, Yen-Chung Hsiue, et al. · Endocrine Connections (2025) | TGRS Research Map | TGRS