Tertiary lymphoid structures in glioblastoma: Association with multiparametric MRI imaging phenotypic features and patient survival
TLSs exist at varying maturation stages in GBM and represent favorable prognostic biomarkers. Their presence and maturity significantly correlate with OS and specific VASARI features. Preoperative imaging prediction of TLSs may facilitate risk stratification and individualized treatment for GBM patients.
Authors
- J. Zhou
- Jiangwei Man
- Qing Zhou (ORCID: https://orcid.org/0000-0002-1917-5105)
- Jia Kang (ORCID: https://orcid.org/0009-0002-4651-9732)
- Xiaoai Ke
- Caiqiang Xue
- Peng Zhang
- Bin Zhang
- Zhiyong Zhao
Institutions
- Qingdao University (CN)
- International Medical and Technological University (TZ)
- Affiliated Hospital of Qingdao University (CN)
- Lanzhou University Second Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1093/noajnl/vdaf263
- Primary Topic
- CNS Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Lanzhou University
- National Natural Science Foundation of China
- Science and Technology Program of Gansu Province