Incidence of Bevacizumab‐Associated Toxicity in Children With Low‐Grade Glioma With and Without Neurofibromatosis Type 1

HTN is more common than previously reported in both NF1 and non-NF1 patients treated with BVZ for LGG, but reversible. Blood pressure should be monitored and treated appropriately. BVZ appears to be a safe and efficacious therapeutic option for young patients with NF1-related optic glioma.

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2025-12-22
DOI
https://doi.org/10.1002/1545-5017.70059
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
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article

Incidence of Bevacizumab‐Associated Toxicity in Children With Low‐Grade Glioma With and Without Neurofibromatosis Type 1

Gilad Hamdani, Alexander Yelak, Helen Toledano, Orli Michaeli et al.
Pediatric Blood & Cancer
Neurofibromatosis and Schwannoma Cases
article

Incidence of Bevacizumab‐Associated Toxicity in Children With Low‐Grade Glioma With and Without Neurofibromatosis Type 1

Gilad Hamdani, Alexander Yelak, Helen Toledano, Orli Michaeli, Amit Dagan, Gad Dotan
article en

Abstract

HTN is more common than previously reported in both NF1 and non-NF1 patients treated with BVZ for LGG, but reversible. Blood pressure should be monitored and treated appropriately. BVZ appears to be a safe and efficacious therapeutic option for young patients with NF1-related optic glioma.

Pediatric Blood & CancerVol. 73(2)
Tel Aviv University (IL), Schneider Children's Medical Center (IL)
Good health and well-being
Openalex Percentile: Top 32%
Neurofibromatosis and Schwannoma Cases
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