Low-dose lipopolysaccharide pretreatment enhanced the proliferation and antibacterial activity of human adipose-derived mesenchymal stem cells

These findings highlight the capacity of LPS preconditioning to potentiate the biological functions of hADSCs, enhancing the antimicrobial and regenerative efficacy of hADSC-CM, and providing a promising strategy for the treatment of chronically infected wounds.

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Publication Details

Journal
Regenerative Therapy
Published
2025-12-22
DOI
https://doi.org/10.1016/j.reth.2025.101057
Primary Topic
Mesenchymal stem cell research
Type
article
Field-Weighted Citation Impact
0.00
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article

Low-dose lipopolysaccharide pretreatment enhanced the proliferation and antibacterial activity of human adipose-derived mesenchymal stem cells

Feng Wang, Xia Wang, Yicai Liu, Linling Li et al.
Regenerative Therapy
Mesenchymal stem cell research
article

Low-dose lipopolysaccharide pretreatment enhanced the proliferation and antibacterial activity of human adipose-derived mesenchymal stem cells

Feng Wang, Xia Wang, Yicai Liu, Linling Li, Xiaoming Fu, Jielin Diao
article en

Abstract

These findings highlight the capacity of LPS preconditioning to potentiate the biological functions of hADSCs, enhancing the antimicrobial and regenerative efficacy of hADSC-CM, and providing a promising strategy for the treatment of chronically infected wounds.

Regenerative TherapyVol. 31
Fuyang City People's Hospital (CN), Yancheng Third People's Hospital (CN), Sichuan Provincial Hospital of Traditional Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 27%
Mesenchymal stem cell research
DOIOpen Access PDFOpenAlex
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Low-dose lipopolysaccharide pretreatment enhanced the proliferation and antibacterial activity of human adipose-derived mesenchymal stem cells — Feng Wang, Xia Wang, et al. · Regenerative Therapy (2025) | TGRS Research Map | TGRS