Guideline for the management of hepatitis B and C infection and subsequent liver disease surveillance (where indicated) in people with congenital bleeding disorders: A joint guideline from the British Society of Haematology and the British Viral Hepa
This is a new British Society of Haematology (BSH) guideline which focuses on the management of hepatitis B and C (HBV and HCV) infection affecting people with bleeding disorders (PwBD), including those who cleared the infection many years previously. It is based on the European Association for the Study of the Liver (EASL) guidance and is a succinct practical guide for haematologists to support joint care with hepatology. It is compatible with the joint international guidance from the European Association for Haemophilia and Allied Disorders, European Haemophilia Consortium, International Society on Thrombosis and Haemostasis (ISTH) and World Federation of Hemophilia 2024. However, it provides more specific guidance on investigations for fibrosis/cirrhosis and thresholds for onwards referral to hepatology in those who cleared HCV historically (either through spontaneous clearance or following effective treatment). The aim of this guideline is to improve the management of this group of patients nationally as well as potentially supporting the management of this group of patients internationally. It also contributes to the delivery of recommendations made by the UK Infected Blood Inquiry 2024.
Authors
- Aspinall Rl
- Mark Gillyon‐Powell
- Martin Scott (ORCID: https://orcid.org/0000-0001-6744-443X)
- P T F Kennedy
- Susan Shapiro
- Neil McDougall
- Tom Pembroke
- Katie Jeffery
- Ashley Brown
Institutions
- National Health Service (GB)
- University of Ulster (GB)
- Imperial College Healthcare NHS Trust (GB)
- Queen Mary University of London (GB)
- Glasgow Royal Infirmary (GB)
- University Hospital of Wales (GB)
- University of Manchester (GB)
- National Institute for Health and Care Excellence (GB)
- Public Health England (GB)
- Portsmouth Hospitals NHS Trust (GB)
- Royal Victoria Hospital (GB)
- Oxford University Hospitals NHS Trust (GB)
- Hepatitis B Foundation (US)
- Royal Victoria Hospital (GB)
- BTG International (United Kingdom) (GB)
Publication Details
- Journal
- British Journal of Haematology
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1111/bjh.70283
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bristol-Myers Squibb
- Pfizer
- Gilead Sciences
- CSL Behring
- Swedish Orphan Biovitrum
- Ipsen
- Chugai Pharmaceutical
- Abbott Diagnostics