Recent Advances in the Bioactive Compounds of Prunes ( <i>Prunus domestica</i>  L.) and Their Health Benefits

ABSTRACT Prunes ( Prunus domestica L.) are increasingly recognized for their multifaceted health benefits, which are derived from their rich bioactive compounds. This review aims to consolidate current research on the nutritional components and biological activities of prunes, emphasizing their potential in health promotion and disease prevention. We explore the diverse bioactive compounds in prunes, including polyphenols, polysaccharides, and sorbitol, and their implications for antioxidant, anti‐inflammatory, and antimicrobial activities. The review also examines prunes' effects on laxation, osteoporosis prevention, immune modulation, and regulation of glycolipid metabolism. Clinical studies and mechanistic insights are discussed to provide a comprehensive understanding of prunes' health benefits. The review concludes that prunes possess significant health benefits, with future research directions focusing on the identification of active compounds, determination of effective doses, mechanistic research, and clinical validation. This scientific basis for prune‐based functional foods and pharmaceuticals development contributes to personalized nutrition strategies, offering a comprehensive overview of prunes' potential in healthcare and disease management.