Pharmacokinetics of intranasal levetiracetam in healthy dogs: a feasible route of administration

Levetiracetam is absorbed via the nasal administration route and could be considered a feasible route of administration for at-home rescue protocols. Although concentrations within the human reference interval were achieved in a majority of dogs, a clinical trial is necessary to determine if this method of administration would be effective in a clinical setting.

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Publication Details

Journal
American Journal of Veterinary Research
Published
2025-12-23
DOI
https://doi.org/10.2460/ajvr.25.10.0366
Primary Topic
Veterinary Pharmacology and Anesthesia
Type
article
Field-Weighted Citation Impact
0.00
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article

Pharmacokinetics of intranasal levetiracetam in healthy dogs: a feasible route of administration

Kamoltip Thungrat, Amanda L. Gross, Kendon Kuo, Katherine Gerken et al.
American Journal of Veterinary Research
Veterinary Pharmacology and Anesthesia
article

Pharmacokinetics of intranasal levetiracetam in healthy dogs: a feasible route of administration

Kamoltip Thungrat, Amanda L. Gross, Kendon Kuo, Katherine Gerken, Tom Jukier, Ewa Królak
article en

Abstract

Levetiracetam is absorbed via the nasal administration route and could be considered a feasible route of administration for at-home rescue protocols. Although concentrations within the human reference interval were achieved in a majority of dogs, a clinical trial is necessary to determine if this method of administration would be effective in a clinical setting.

American Journal of Veterinary Research
Auburn University (US)
Openalex Percentile: Top 28%
Veterinary Pharmacology and Anesthesia
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Pharmacokinetics of intranasal levetiracetam in healthy dogs: a feasible route of administration — Kamoltip Thungrat, Amanda L. Gross, et al. · American Journal of Veterinary Research (2025) | TGRS Research Map | TGRS