M2 macrophage infiltration associated with CXCL8 predicts grade 4 prognosis and differentiates glioma grades
CXCL8 has a significant impact on disease prognosis and tumor immunity in Gr. 4 gliomas. The association of CXCL8 with M2 macrophage infiltration suggests that CXCL8-related markers could serve as potential prognostic biomarkers for differentiating between Gr. 4 and Gr. 3 gliomas.
Authors
- Cheng-Chin Lee
- A. W. Lee
- Tuan Ngoc Anh Vo (ORCID: https://orcid.org/0000-0002-1087-9114)
- Yung-Fu Wu (ORCID: https://orcid.org/0000-0002-6920-7689)
- W. H. Liu
- Chien-Yu Huang (ORCID: https://orcid.org/0000-0002-2340-6148)
- Yu-Jia Chang
- Jang-Chun Lin
Institutions
- National Tsing Hua University (TW)
- Wan Fang Hospital (TW)
- Taipei Medical University-Shuang Ho Hospital (TW)
- Ho Chi Minh City University of Technology (VN)
- Taipei Medical University (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1007/s12672-025-03982-2
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tri-Service General Hospital
- National Science and Technology Council
- Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare