Red cell distribution width and related indices in relation to target-organ damage in children with hypertension

Elevated RDW and RPR levels were associated with LVH in hypertensive children, suggesting their potential role as markers of target organ damage, whereas RAR showed limited utility. Male gender emerged as an independent risk factor for LVH. Obese children demonstrated higher leukocyte counts, indicating a link between obesity and systemic inflammation. However, RDW and RAR did not vary with BMI, and unexpectedly, RPR was higher in children with normal BMI. These findings suggest that hematological parameters may provide insights into both cardiovascular risk and obesity-related changes in pediatric populations.

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Journal
BMC Pediatrics
Published
2025-12-23
DOI
https://doi.org/10.1186/s12887-025-06349-2
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
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article
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article

Red cell distribution width and related indices in relation to target-organ damage in children with hypertension

Nuriye Boduc Bolu, Nesrin Taş, Arife Uslu Gökçeoğlu
BMC Pediatrics
Inflammatory Biomarkers in Disease Prognosis
article

Red cell distribution width and related indices in relation to target-organ damage in children with hypertension

Nuriye Boduc Bolu, Nesrin Taş, Arife Uslu Gökçeoğlu
article en

Abstract

Elevated RDW and RPR levels were associated with LVH in hypertensive children, suggesting their potential role as markers of target organ damage, whereas RAR showed limited utility. Male gender emerged as an independent risk factor for LVH. Obese children demonstrated higher leukocyte counts, indicating a link between obesity and systemic inflammation. However, RDW and RAR did not vary with BMI, and unexpectedly, RPR was higher in children with normal BMI. These findings suggest that hematological parameters may provide insights into both cardiovascular risk and obesity-related changes in pediatric populations.

BMC PediatricsVol. 25(1)
Ministry of Health (TR), Memorial Ankara Hospital (TR), Ankara Numune Eğitim ve Araştırma Hastanesi (TR), Alanya University (TR)
Gender equality
Openalex Percentile: Top 32%
Inflammatory Biomarkers in Disease Prognosis
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Red cell distribution width and related indices in relation to target-organ damage in children with hypertension — Nuriye Boduc Bolu, Nesrin Taş, et al. · BMC Pediatrics (2025) | TGRS Research Map | TGRS