Phlegmasia Cerulea Dolens as an Initial Presentation of Ovarian Cancer

Phlegmasia cerulea dolens (PCD) is a syndrome which is characterized by the presence of sudden severe pain, swelling, and purple or bluish discoloration of either upper or lower limbs. It is rare but can be often fatal form of venous thromboembolism and may result in venous gangrene, pulmonary embolism, shock, and death. We report an elderly female who had PCD as an initial presentation of highly suspected ovarian cancer. To date, this is the first case report of PCD as an initial presentation of ovarian cancer we could find in medical literature. Our key clinical message is to report the association of ovarian cancer with PCD.

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Journal
Journal of Applied Hematology
Published
2025-10-01
DOI
https://doi.org/10.4103/joah.joah_88_25
Primary Topic
Skin Diseases and Diabetes
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article

Phlegmasia Cerulea Dolens as an Initial Presentation of Ovarian Cancer

Mohammed Abdulhameed Albalawi
Journal of Applied Hematology
Skin Diseases and Diabetes
article

Phlegmasia Cerulea Dolens as an Initial Presentation of Ovarian Cancer

Mohammed Abdulhameed Albalawi
article en

Abstract

Phlegmasia cerulea dolens (PCD) is a syndrome which is characterized by the presence of sudden severe pain, swelling, and purple or bluish discoloration of either upper or lower limbs. It is rare but can be often fatal form of venous thromboembolism and may result in venous gangrene, pulmonary embolism, shock, and death. We report an elderly female who had PCD as an initial presentation of highly suspected ovarian cancer. To date, this is the first case report of PCD as an initial presentation of ovarian cancer we could find in medical literature. Our key clinical message is to report the association of ovarian cancer with PCD.

Journal of Applied HematologyVol. 16(4)
Taibah University (SA), Islamic University of Madinah (SA)
Good health and well-being
Openalex Percentile: Top 25%
Skin Diseases and Diabetes
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