The impact of <i>APOE</i> ε4 on cognition in Brazilians with type 2 diabetes: exploring ethnicity effects
<i>APOE</i> ε4 was not linked to cognitive errors in the full T2D Brazilian cohort.Trend toward fewer MMSE errors among self-reported Black/Brown <i>APOE</i> ε4 carriers.Higher education, physical activity, and BMI were protective against MMSE errors.Black/Brown race and older age were associated with more MMSE errors.Results support multifactorial assessment and more studies in admixed T2D populations.
Authors
- Mozânia Reis de Matos (ORCID: https://orcid.org/0000-0002-4434-9170)
- Sueli Mieko Oba‐Shinjo (ORCID: https://orcid.org/0000-0002-1650-5973)
- Miyuki Uno (ORCID: https://orcid.org/0000-0003-2589-6432)
- Paula R. Sola (ORCID: https://orcid.org/0000-0001-6452-1436)
- Bruno Fukelmann Guedes (ORCID: https://orcid.org/0000-0001-8391-2117)
- Sônia Maria Dozzi Brucki (ORCID: https://orcid.org/0000-0002-8303-6732)
- Sharon Sanz Simon (ORCID: https://orcid.org/0000-0003-2603-6215)
- Marisa Passarelli
- Rafael Lara Nohmi
- Suely Kazue Nagahashi Marie
- Michal Schnaider Beeri
- Maria Lucia Correa‐Giannella
Institutions
- Rutgers, The State University of New Jersey (US)
- Universidade de São Paulo (BR)
- Johnson University (US)
- Universidade Nove de Julho (BR)
- Instituto do Câncer do Estado de São Paulo (BR)
- Environmental and Occupational Health Sciences Institute (US)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/dad2.70231
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Conselho Nacional de Desenvolvimento Científico e Tecnológico