Blood biomarkers of response to concomitant intratympanic and systemic corticosteroids treatment for idiopathic sudden sensorineural hearing loss
In patients with ISSNHL treated with dual-route corticosteroids, several clinical and hematologic factors, particularly elevated PLR and delayed treatment, are independently associated with reduced odds of hearing recovery. Inflammatory blood markers may serve as accessible prognostic tools to support early risk stratification.
Authors
- Giancarlo Tirelli
- Ludovica Costariol (ORCID: https://orcid.org/0000-0002-3337-4725)
- Paolo Boscolo-Rizzo (ORCID: https://orcid.org/0000-0002-4635-7959)
- Federico Cavallo-Ronchi
- Simone Zucchini
- Egidio Sia
Institutions
- University of Trieste (IT)
- Ospedale di Cattinara (IT)
Publication Details
- Journal
- European Archives of Oto-Rhino-Laryngology
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1007/s00405-025-09904-w
- Citations
- 1
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.84