Identification of salivary volatile organic compounds as the potential diagnostic markers of oral cancer by the gas chromatography–mass spectrometry analysis

The study demonstrates that salivary VOC profiling can reveal distinct metabolomic alterations in OSCC and OPMDs, with several VOCs emerging as potential tumor-specific biomarkers. While these findings highlight the promise of VOC-based screening, larger studies are needed to validate these markers and establish their clinical applicability.

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Publication Details

Journal
Dental and Medical Problems
Published
2025-12-22
DOI
https://doi.org/10.17219/dmp/178326
Primary Topic
Advanced Chemical Sensor Technologies
Type
article
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article

Identification of salivary volatile organic compounds as the potential diagnostic markers of oral cancer by the gas chromatography–mass spectrometry analysis

P. Vijay Kumar, Ruchika Chaudhary, Shwetha Venkataramana, Sujatha SAMPIGE REDDY et al.
Dental and Medical Problems
Advanced Chemical Sensor Technologies
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Identification of salivary volatile organic compounds as the potential diagnostic markers of oral cancer by the gas chromatography–mass spectrometry analysis

P. Vijay Kumar, Ruchika Chaudhary, Shwetha Venkataramana, Sujatha SAMPIGE REDDY, Sreekanth PUTHUPARAMBIL Kunjumon, NAGARAJU RAKESH, LAIPUBAM FABINA SHARMA, Vaishnavi PALANISAMY
article en

Abstract

The study demonstrates that salivary VOC profiling can reveal distinct metabolomic alterations in OSCC and OPMDs, with several VOCs emerging as potential tumor-specific biomarkers. While these findings highlight the promise of VOC-based screening, larger studies are needed to validate these markers and establish their clinical applicability.

Dental and Medical ProblemsVol. 62(6)
ASTER (CA), Manubhai Patel Dental College and Hospital (IN), M S Ramaiah University of Applied Sciences (IN), Orthopaedic Research Group (IN), Government Dental College and Hospital (IN)
Good health and well-being
Openalex Percentile: Top 43%
Advanced Chemical Sensor Technologies
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