Surgery versus stereotactic body radiotherapy for oligometastatic colorectal cancer: a prospective cohort study with propensity score matching

In oligometastatic CRC, surgical resection is associated with a significant overall survival advantage compared to SBRT, albeit with increased upfront morbidity, resource use, and initial QoL impairment. SBRT offers a favorable safety profile and minimal short-term disruption with comparable local control. The choice between modalities represents a critical trade-off, underscoring the need for personalized, patient-centric decision-making.