Dose optimization of linezolid among surgical patients: A population pharmacokinetic study

The renal status and age of the patients are significant covariates responsible for linezolid CL, and a dose of 200, 300, 400, and 600 mg is appropriate for patients with CrCl of 20, 40, 80, and 120 mL/min, respectively.

Authors

Publication Details

Journal
International Journal of Clinical Pharmacology and Therapeutics
Published
2025-12-22
DOI
https://doi.org/10.5414/cp204889
Primary Topic
Antimicrobial Resistance in Staphylococcus
Type
article
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0.00
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article

Dose optimization of linezolid among surgical patients: A population pharmacokinetic study

Hajira Bilal, Walaa Alsanie, Muhammad Naeem Aamir, Abdulhakeem S Alamri et al.
International Journal of Clinical Pharmacology and Therapeutics
Antimicrobial Resistance in Staphylococcus
article

Dose optimization of linezolid among surgical patients: A population pharmacokinetic study

Hajira Bilal, Walaa Alsanie, Muhammad Naeem Aamir, Abdulhakeem S Alamri, Muhammad Usman, Mustajab Ali Naseer
article en

Abstract

The renal status and age of the patients are significant covariates responsible for linezolid CL, and a dose of 200, 300, 400, and 600 mg is appropriate for patients with CrCl of 20, 40, 80, and 120 mL/min, respectively.

International Journal of Clinical Pharmacology and TherapeuticsVol. 64(04)
Openalex Percentile: Top 31%
Antimicrobial Resistance in Staphylococcus
DOISourceOpenAlex
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Dose optimization of linezolid among surgical patients: A population pharmacokinetic study — Hajira Bilal, Walaa Alsanie, et al. · International Journal of Clinical Pharmacology and Therapeutics (2025) | TGRS Research Map | TGRS