Airway transcriptome networks for ozone and PM2.5 exposure reveal distinct key drivers for children with asthma
Children with and without asthma have very distinct causal networks and key drivers for ozone and PM<sub>2.5</sub> exposure. The identified key drivers represent high-yield targets for intervention and treatment of pollutant-exacerbated asthma.
Authors
- Haritz Irizar (ORCID: https://orcid.org/0000-0002-8413-406X)
- Kyle B. Reed (ORCID: https://orcid.org/0000-0003-0848-8971)
- Galina Grishina
- Alexander Grishin (ORCID: https://orcid.org/0000-0003-4799-4324)
- Lingdi Zhang (ORCID: https://orcid.org/0000-0002-9146-8308)
- Alfin Vicencio
- Supinda Bunyavanich
- Yoojin Chun
Institutions
- Hackensack Meridian Health (US)
- Center for Discovery (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Genome Medicine
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1186/s13073-025-01570-1
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Georgia Clinical and Translational Science Alliance
- National Institutes of Health
- National Center for Advancing Translational Sciences