Personalized MASLD and liver fibrosis risk assessment for adults: glycemic status determines optimal choice of non-invasive indices

Glycemic deterioration is strongly linked to MASLD and fibrosis. TyG-WC and FLI were the most consistent and high-performing indices across glycemic and demographic groups, supporting their use as broadly applicable non-invasive tools for individualized MASLD risk assessment.

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Publication Details

Journal
Diabetology & Metabolic Syndrome
Published
2025-12-22
DOI
https://doi.org/10.1186/s13098-025-02069-w
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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Personalized MASLD and liver fibrosis risk assessment for adults: glycemic status determines optimal choice of non-invasive indices

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Personalized MASLD and liver fibrosis risk assessment for adults: glycemic status determines optimal choice of non-invasive indices

Jiacheng Cheng, Dongyu Hu, Junhua He, Jin Li, Yuan Zhao, Yikun Zhu, Huili Cao, Xiaojuan Wang
article en

Abstract

Glycemic deterioration is strongly linked to MASLD and fibrosis. TyG-WC and FLI were the most consistent and high-performing indices across glycemic and demographic groups, supporting their use as broadly applicable non-invasive tools for individualized MASLD risk assessment.

Diabetology & Metabolic SyndromeVol. 17(1)
Shanxi Medical University (CN), Second Hospital of Shanxi Medical University (CN)
Zero hunger
Openalex Percentile: Top 31%
Liver Disease Diagnosis and Treatment
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