Real-world evaluation of ceftriaxone-related safety events: a stewardship call to action

A ceftriaxone safety alert prompted a review of rapid response and cardiac arrest events in relation to the timing of intravenous cephalosporin administrations across a large health system. Despite high utilization, we found a low rate of significant ceftriaxone-related adverse events with a similar incidence as other intravenous cephalosporins.

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Publication Details

Journal
Antimicrobial Stewardship & Healthcare Epidemiology
Published
2025-12-22
DOI
https://doi.org/10.1017/ash.2025.10258
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
Field-Weighted Citation Impact
0.00
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article

Real-world evaluation of ceftriaxone-related safety events: a stewardship call to action

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Real-world evaluation of ceftriaxone-related safety events: a stewardship call to action

Kristen Paciullo, Sarah B. Green, Leila S Hojat, Daniel Rogers, Sujit Suchindran, K. Ashley Jones, Benjamin Albrecht, Lucy S. Witt, Trinh P. Vu
article en

Abstract

A ceftriaxone safety alert prompted a review of rapid response and cardiac arrest events in relation to the timing of intravenous cephalosporin administrations across a large health system. Despite high utilization, we found a low rate of significant ceftriaxone-related adverse events with a similar incidence as other intravenous cephalosporins.

Antimicrobial Stewardship & Healthcare EpidemiologyVol. 6(1)
Emory Healthcare (US), Emory University (US)
Openalex Percentile: Top 31%
Antibiotics Pharmacokinetics and Efficacy
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