Which Prediction Works Best? A 3-Dimensional Evaluation of Mixed Dentition Analysis in Cleft Lip and Palate

ObjectiveThis study aimed to evaluate the accuracy of different mixed dentition period analysis methods in individuals with cleft lip and palate (CLP).DesignRetrospective comparative study.SettingDepartment of Orthodontics, Erciyes University, Turkiye.Patients/ParticipantsA total of 70 individuals aged 13 to 16 years were included in the study: 35 with CLP and 35 noncleft controls. In all individuals included in the study, all permanent teeth had erupted except for the maxillary lateral incisors, which are frequently missing in individuals with CLP.InterventionsFor formulas suggested by 8 different prediction methods (Tanaka-Johnston, Moyers 50%, Moyers 75%, Boboc, Cattaneo, Camilo, Barnabe, and Melgaço), the MD and buccolingual dimensions of incisors and molars, as well as the mesiodistal dimensions of erupted canines and premolars, were measured on the 3-dimensional dental models.Main Outcome MeasuresComparison of mean difference between actual and predicted permanent canine and premolar widths, using the control sample as a benchmark to judge model suitability in the CLP population.ResultsAll regression methods showed significant differences between predicted and actual values in the CLP group (<i>P</i> < .05). Boboc and Cattaneo had the fewest errors, while Tanaka-Johnston and Barnabé showed the most significant overestimation. In controls, Cattaneo was most accurate in the maxilla and Tanaka-Johnston in the mandible.ConclusionsThe Boboc and Cattaneo methods provided the most accurate predictions of permanent canine and premolar widths in patients with CLP, while the Tanaka-Johnston and Barnabé methods consistently overestimated values.