Pregabalin acts on Na+–Ca2+ exchanger, which promotes Ca2+ extrusion from human Merkel cell line

These results suggested that the site of action of pregabalin to MCs is Ca<sup>2+</sup> extrusion mechanism via NCX1.

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Publication Details

Journal
PAIN Reports
Published
2025-12-18
DOI
https://doi.org/10.1097/pr9.0000000000001381
Primary Topic
Ion channel regulation and function
Type
article
Field-Weighted Citation Impact
0.00
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article

Pregabalin acts on Na+–Ca2+ exchanger, which promotes Ca2+ extrusion from human Merkel cell line

Hidetaka KURODA, Tatsuya Ichinohe, Rumi Kaneko, Maki Kimura et al.
PAIN Reports
Ion channel regulation and function
article

Pregabalin acts on Na+–Ca2+ exchanger, which promotes Ca2+ extrusion from human Merkel cell line

Hidetaka KURODA, Tatsuya Ichinohe, Rumi Kaneko, Maki Kimura, Yoshiyuki Shibukawa, Takehito Ouchi
article en

Abstract

These results suggested that the site of action of pregabalin to MCs is Ca<sup>2+</sup> extrusion mechanism via NCX1.

PAIN ReportsVol. 11(1)
Tokyo Dental College (JP), Kanagawa Dental University (JP)
Openalex Percentile: Top 37%
Ion channel regulation and function
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Pregabalin acts on Na+–Ca2+ exchanger, which promotes Ca2+ extrusion from human Merkel cell line — Hidetaka KURODA, Tatsuya Ichinohe, et al. · PAIN Reports (2025) | TGRS Research Map | TGRS