Pregabalin acts on Na+–Ca2+ exchanger, which promotes Ca2+ extrusion from human Merkel cell line
These results suggested that the site of action of pregabalin to MCs is Ca<sup>2+</sup> extrusion mechanism via NCX1.
Authors
- Hidetaka KURODA
- Tatsuya Ichinohe (ORCID: https://orcid.org/0000-0001-5793-3379)
- Rumi Kaneko
- Maki Kimura
- Yoshiyuki Shibukawa
- Takehito Ouchi
Institutions
- Tokyo Dental College (JP)
- Kanagawa Dental University (JP)
Publication Details
- Journal
- PAIN Reports
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1097/pr9.0000000000001381
- Primary Topic
- Ion channel regulation and function
- Type
- article
- Field-Weighted Citation Impact
- 0.00