A Concise Total Synthesis of (+)-Pedrolide
A concise total synthesis of (+)-pedrolide has been accomplished. Key steps include an intramolecular Diels-Alder reaction to rapidly construct the tetracyclic carbon skeleton from <i>(R)-</i>carvone and the late-stage application of two different MHAT reactions in advancing the highly functionalized carane moiety.
Authors
- John L. Wood (ORCID: https://orcid.org/0000-0002-9066-5588)
- Yushang Zhou
- Hao Shen
Institutions
- Baylor University (US)
Publication Details
- Journal
- Journal of the American Chemical Society
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1021/jacs.5c17555
- Citations
- 1
- Primary Topic
- Synthetic Organic Chemistry Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.94