Patient experience and clinical outcome assessment validity in amyotrophic lateral sclerosis: a targeted literature review
This review identified wide-ranging symptoms and HRQoL impacts experienced by people with ALS, but detailed qualitative evidence is sparse. Multiple COAs were identified as potential measures in ALS clinical trials.
Authors
- Laure Delbecque
- Jessica Flynn (ORCID: https://orcid.org/0000-0002-4461-2610)
- Sophi Tatlock (ORCID: https://orcid.org/0000-0002-4959-9822)
- Ekin Seçinti (ORCID: https://orcid.org/0000-0001-7794-8500)
- Sarah E. Curtis
- Nicole F. Mehdiyoun
- Louise O’Hara
- Lara Ayala-Nunes
- Katherine Fernelius
- Nicola Hodson
Institutions
- Eli Lilly (United States) (US)
- Adelphi Laboratory Center (US)
Publication Details
- Journal
- Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1080/21678421.2025.2604233
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00