Multiparameter MRI assessment of metformin and exercise effects on skeletal muscle in prediabetes: a randomized controlled trial
Aerobic exercise improves muscle composition and glucose metabolism in prediabetes. Metformin adds benefits for reducing muscle fat in high-fat individuals. Multiparameter MRI enables noninvasive monitoring of skeletal muscle metabolic changes.
Authors
- Xiaohong Lyu (ORCID: https://orcid.org/0000-0002-4647-7758)
- Xianghong Yang
- Fuyao Yu
- Chuan Xing (ORCID: https://orcid.org/0000-0002-1375-4958)
- Shinong Pan
- Nan Ye
- Yue Chen (ORCID: https://orcid.org/0009-0009-6681-1459)
- Yanbin Dong
Institutions
- Augusta University (US)
- Prevention Institute (US)
- Affiliated Hospital of Hangzhou Normal University (CN)
- Liaoning Provincial People's Hospital (CN)
- Jinzhou Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- European Radiology Experimental
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1186/s41747-025-00658-y
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Medical University
- Department of Education of Liaoning Province
- Shengjing Hospital