Comparison of two established approaches for generating Hounsfield look‐up tables for CT‐based SPR prediction

The established HLUT generation methods for CT-based SPR prediction developed in Japan and Europe were compared and showed good agreement across all tissue types. Range differences in clinical cases were minor, and ΔSPR variations in cortical bone corresponded to negligible proton range deviations. These findings indicate that the European and Japanese approaches are practically equivalent and support the validity and reliability of the HIPRAC-CTCA method.

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Publication Details

Journal
Medical Physics
Published
2025-12-21
DOI
https://doi.org/10.1002/mp.70236
Primary Topic
Advanced Radiotherapy Techniques
Type
article
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article

Comparison of two established approaches for generating Hounsfield look‐up tables for CT‐based SPR prediction

Christian Richter, Minoru Nakao, Nils Peters, Julian Schwengfelder et al.
Medical Physics
Advanced Radiotherapy Techniques
article

Comparison of two established approaches for generating Hounsfield look‐up tables for CT‐based SPR prediction

Christian Richter, Minoru Nakao, Nils Peters, Julian Schwengfelder, Shuichi Ozawa
article en

Abstract

The established HLUT generation methods for CT-based SPR prediction developed in Japan and Europe were compared and showed good agreement across all tissue types. Range differences in clinical cases were minor, and ΔSPR variations in cortical bone corresponded to negligible proton range deviations. These findings indicate that the European and Japanese approaches are practically equivalent and support the validity and reliability of the HIPRAC-CTCA method.

Medical PhysicsVol. 53(1)
Hiroshima University (JP), Helmholtz-Zentrum Dresden-Rossendorf (DE), Massachusetts General Hospital (US), Fred Hutch Cancer Center (US), OncoRay (DE), University Hospital Carl Gustav Carus (DE)
Partnerships for the goals
Openalex Percentile: Top 27%
Advanced Radiotherapy Techniques
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