Case Report of an Unusual Combination of Perineal Leiomyosarcoma with Uterine Adenocarcinoma and Leiomyoma

REPORTtwo large intramural leiomyomas.Biopsy from the perineal mass suggested high-grade mesenchymal sarcoma [smooth muscle actin (SMA) positive and vimentin focally positive].Endometrial aspiration indicated high-grade adenocarcinoma.Differentials included endometrial carcinoma metastasis, Bartholin cyst, and primary soft-tissue tumor.A diagnosis of perineal leiomyosarcoma with synchronous endometrial adenocarcinoma was established.

Authors

Publication Details

Journal
Journal of Medical Academics
Published
2025-12-20
DOI
https://doi.org/10.5005/jp-journals-11003-0196
Primary Topic
Urologic and reproductive health conditions
Type
article
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article

Case Report of an Unusual Combination of Perineal Leiomyosarcoma with Uterine Adenocarcinoma and Leiomyoma

Astha Nayyar, Anurag Mishra, Vibha Singh
Journal of Medical Academics
Urologic and reproductive health conditions
article

Case Report of an Unusual Combination of Perineal Leiomyosarcoma with Uterine Adenocarcinoma and Leiomyoma

Astha Nayyar, Anurag Mishra, Vibha Singh
article en

Abstract

REPORTtwo large intramural leiomyomas.Biopsy from the perineal mass suggested high-grade mesenchymal sarcoma [smooth muscle actin (SMA) positive and vimentin focally positive].Endometrial aspiration indicated high-grade adenocarcinoma.Differentials included endometrial carcinoma metastasis, Bartholin cyst, and primary soft-tissue tumor.A diagnosis of perineal leiomyosarcoma with synchronous endometrial adenocarcinoma was established.

Journal of Medical AcademicsVol. 8(2)
Good health and well-being
Openalex Percentile: Top 28%
Urologic and reproductive health conditions
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Case Report of an Unusual Combination of Perineal Leiomyosarcoma with Uterine Adenocarcinoma and Leiomyoma — Astha Nayyar, Anurag Mishra, et al. · Journal of Medical Academics (2025) | TGRS Research Map | TGRS