SLC25A39 identified as a key regulator of hepatocellular carcinoma progression through the mitochondrial ROS–cytochrome c–caspase signaling axis
Our study reveals SLC25A39 as a critical regulator of HCC progression via the mitochondrial ROS-cytochrome c-caspase signaling axis, highlighting its potential as a diagnostic biomarker and therapeutic target in HCC.
Authors
- R. Li
- Qi Shen (ORCID: https://orcid.org/0000-0002-1399-3350)
- Jinyang Wang
- Chengbin Wang
- Manqiu Yuan
- Tian Xia
- Meng Du
- Jiachi Yu
Institutions
- Xuzhou Medical College (CN)
- Nankai University (CN)
- Chinese PLA General Hospital (CN)
- Second People’s Hospital of Huai’an (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Cellular & Molecular Biology Letters
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1186/s11658-025-00829-0
- Primary Topic
- Cell death mechanisms and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00