The impact of tizanidine, thiocolchicoside, and cyclobenzaprine on vascular function in ovariectomized rats
TZ cannot be considered a safe medication for patients with endothelial dysfunction. In high doses and for longer periods, TCC and CBZ might also have deleterious effects on vascular reactivity. These findings are noteworthy from the perspective of rational drug therapy.
Authors
- Buket Demirci (ORCID: https://orcid.org/0000-0002-3442-5061)
- Uğur Berkay İnce
- Tolga Esmerligil
- SÜMEYYE NUR GÜRSOY
- TURHAN DOST
Institutions
- Adnan Menderes University (TR)
Publication Details
- Journal
- TURKISH JOURNAL OF MEDICAL SCIENCES
- Published
- 2025-12-12
- DOI
- https://doi.org/10.55730/1300-0144.6115
- Primary Topic
- Nitric Oxide and Endothelin Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00