Chitosan-PVA microneedle-assisted continuous transdermal administration of triamcinolone acetonide for the treatment of granulomatous mastitis
The MNs@TA-CS achieves comparable efficacy to traditional injections while offering sustained drug release and minimized systemic exposure. Its biphasic release mode provides both rapid onset and prolonged therapeutic effect, making it a promising minimally invasive, patient-friendly alternative for GM treatment.
Authors
- Rong Huang (ORCID: https://orcid.org/0000-0002-2095-3883)
- Yuqi Liang (ORCID: https://orcid.org/0000-0002-7481-116X)
- Y Li
- Yan Dai
- Juan Lin (ORCID: https://orcid.org/0000-0002-9290-3631)
- L Wang
- Fengjie Bie (ORCID: https://orcid.org/0000-0001-7184-7514)
- Ping Huang (ORCID: https://orcid.org/0000-0002-1012-9997)
- Qianqian Guo (ORCID: https://orcid.org/0000-0003-1510-6070)
- Jun-Feng Huang
- Cong-Wen Yang
- Qian-Jun Chen
- Biao Xu
- Ru-Dong Chen
- Ying-Shuai Wang
- Yi-Shan Pan
Institutions
- Weifang Medical University (CN)
- Guangzhou University of Chinese Medicine (CN)
- State Administration of Traditional Chinese Medicine of the People's Republic of China (CN)
- Second Hospital of Shandong University (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- Ningxia Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1097/js9.0000000000004612
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00