<scp>BK</scp> Polyomavirus in Pediatric Kidney Transplant Recipients: Incidence, Risk Factors, <scp>dnDSA</scp> Development, and the Role of <scp>IVIG</scp>
The findings of our study suggest a potential benefit of stringent BKV screening and considering timely and intensive treatments before graft dysfunction becomes apparent. Our research also indicates that IVIG might be effective in managing both confirmed and presumptive BKVAN cases, as evidenced by the similar graft outcome observed after a 3-year follow-up period post BKV DNAmia. Notably, despite more frequent adjustments to immunosuppressants and a higher rate of human leukocyte antigen (HLA) mismatch in the BKV DNAemia group, the incidence of dnDSA formation appeared to be comparable between the two groups. These observations warrant controlled trials to confirm their broad applicability.
Authors
- A. azzam
- Mohammed Almaghrabi (ORCID: https://orcid.org/0000-0003-4929-7071)
- Alanoud Alshami (ORCID: https://orcid.org/0000-0002-6199-5174)
- Ammar Hamed
- Abeer Alessa
- Hebatalla Bahbah
- Nasreen Mohammed
Institutions
- King Fahad Specialist Hospital (SA)
Publication Details
- Journal
- Pediatric Transplantation
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1111/petr.70255
- Primary Topic
- Polyomavirus and related diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00