Umbilical Anomalies and Exomphalos: A Review of Current Practice

Abstract Objective: To review current practice in the diagnosis and management of umbilical anomalies, with emphasis on exomphalos. Design: Narrative review of published literature and clinical guidelines. Results: Umbilical anomalies range from minor hernia of the cord to giant exomphalos. Antenatal diagnosis is feasible with ultrasound and MRI. Management strategies vary from primary closure to staged silo reduction and conservative epithelisation. Prognosis depends on defect size, liver involvement, and associated anomalies. Conclusions: Exomphalos remains a major neonatal surgical challenge. Current practice balances surgical innovation with conservative approaches, but consensus guidelines are lacking.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-12-05
DOI
https://doi.org/10.5281/zenodo.18001330
Primary Topic
Congenital Anomalies and Fetal Surgery
Type
article
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article

Umbilical Anomalies and Exomphalos: A Review of Current Practice

Patel Reenal R, Govani Nd, Singh SJ, Midha PK et al.
Zenodo (CERN European Organization for Nuclear Research)
Congenital Anomalies and Fetal Surgery
article

Umbilical Anomalies and Exomphalos: A Review of Current Practice

Patel Reenal R, Govani Nd, Singh SJ, Midha PK, Mehta AR, Zaparackaite I, Patel RV, Singh H
article en

Abstract

Abstract Objective: To review current practice in the diagnosis and management of umbilical anomalies, with emphasis on exomphalos. Design: Narrative review of published literature and clinical guidelines. Results: Umbilical anomalies range from minor hernia of the cord to giant exomphalos. Antenatal diagnosis is feasible with ultrasound and MRI. Management strategies vary from primary closure to staged silo reduction and conservative epithelisation. Prognosis depends on defect size, liver involvement, and associated anomalies. Conclusions: Exomphalos remains a major neonatal surgical challenge. Current practice balances surgical innovation with conservative approaches, but consensus guidelines are lacking.

Zenodo (CERN European Organization for Nuclear Research)
Nottingham University Hospitals NHS Trust (GB), RK University (IN), Mount Sinai Hospital (US), Evelina London Children's Healthcare (GB), Cardiovascular Medical Group (US)
Industry, innovation and infrastructure
Openalex Percentile: Top 27%
Congenital Anomalies and Fetal Surgery
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