The Impact of Antidepressant Medications on Sleep in Children

Antidepressants are increasingly prescribed for pediatric patients to treat a vast array of mental health conditions, including anxiety disorders, depressive disorders, and obsessive-compulsive disorder (OCD). While there is extensive research supporting the efficacy of antidepressants in managing these conditions in the pediatric population, their effects on sleep, an essential component of overall well-being, remain a critical area of interest. This review explores the clinical effects on sleep disorders and the impact of antidepressants on sleep architecture and overall sleep quality in children and adolescents. Further investigation involving longitudinal studies, antidepressant medication comparison, and multifaceted approaches would provide insight into evaluating the impact of certain classes of antidepressants on overall sleep quality.

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Publication Details

Journal
Journal of Clinical Psychopharmacology
Published
2025-12-22
DOI
https://doi.org/10.1097/jcp.0000000000002113
Primary Topic
Sleep and related disorders
Type
article
Field-Weighted Citation Impact
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article

The Impact of Antidepressant Medications on Sleep in Children

Lourdes M. DelRosso, Brianna Alconcher, Jason Simbre, David Zakharyan et al.
Journal of Clinical Psychopharmacology
Sleep and related disorders
article

The Impact of Antidepressant Medications on Sleep in Children

Lourdes M. DelRosso, Brianna Alconcher, Jason Simbre, David Zakharyan, Mary Anne Tablizo
article en

Abstract

Antidepressants are increasingly prescribed for pediatric patients to treat a vast array of mental health conditions, including anxiety disorders, depressive disorders, and obsessive-compulsive disorder (OCD). While there is extensive research supporting the efficacy of antidepressants in managing these conditions in the pediatric population, their effects on sleep, an essential component of overall well-being, remain a critical area of interest. This review explores the clinical effects on sleep disorders and the impact of antidepressants on sleep architecture and overall sleep quality in children and adolescents. Further investigation involving longitudinal studies, antidepressant medication comparison, and multifaceted approaches would provide insight into evaluating the impact of certain classes of antidepressants on overall sleep quality.

Journal of Clinical PsychopharmacologyVol. 46(1)
Lucile Packard Children's Hospital (US), Palo Alto University (US), University of California, San Francisco (US), University of California, Irvine (US), University of California System (US), Irvine University (US), University of California, Berkeley (US)
Good health and well-being
Openalex Percentile: Top 31%
Sleep and related disorders
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The Impact of Antidepressant Medications on Sleep in Children — Lourdes M. DelRosso, Brianna Alconcher, et al. · Journal of Clinical Psychopharmacology (2025) | TGRS Research Map | TGRS