Standardized Thalassotherapy Versus Conventional Rehabilitation in Post-Traumatic Patients: Clinical, Biochemical, and Quality-of-Life Outcomes

<b>Background:</b> Thalassotherapy, which combines seawater, marine mud, and maritime climate, has been traditionally used to support musculoskeletal recovery. Its thermal, biochemical, and mechanical properties may enhance tissue healing and modulate inflammation. This study aimed to evaluate the short-term clinical effects of a standardized two-week thalassotherapy program compared with conventional rehabilitation in post-traumatic patients. <b>Methods:</b> A matched controlled cohort study was conducted at the Corpore Sano Sanatorium, Techirghiol, Romania. Post-traumatic patients followed identical physiotherapy and hydrokinetic exercise routines; additionally, the thalassotherapy group received daily seawater baths, sapropelic mud applications, and exposure to marine aerosols. Pain levels, joint mobility, inflammatory status, and quality of life were assessed before and after the intervention. Adverse events and treatment tolerance were monitored throughout the study. <b>Results:</b> Patients undergoing thalassotherapy experienced more pronounced improvements in musculoskeletal function, pain relief, inflammatory balance, and quality-of-life outcomes compared with those receiving standard rehabilitation alone. Both interventions contributed to clinical progress, but the magnitude of change was consistently greater among patients treated with marine-based therapies. No adverse events or intolerance reactions were recorded, and all participants completed the program. <b>Conclusions:</b> Thalassotherapy may provide complementary short-term benefits in post-traumatic rehabilitation, enhancing functional recovery, symptom relief, and perceived well-being. However, due to the non-randomized design and short follow-up period, these findings should be interpreted cautiously. Further randomized studies with long-term outcomes are required to confirm the therapeutic role of thalassotherapy in modern rehabilitation practice.